This is a very active, powerful, and useful remedy, and appears to fulfil a great number of indications. It possesses an undoubted influence over the nervous system. In small doses the appetite and digestion are improved, and larger amounts augment the secretions of the gastro-intestinal tract. Excretions from the skin and kidneys are increased by it, the peculiar earthy odor of the drug being imparted to the urine; the secretions of the bronchial mucous surfaces are also augmented under its administration. Upon the heart and circulatory system its effects have been compared to those of digitalis, though being much less pronounced. The heart-beat is slowed and given increased power by it, while arterial tension is elevated. In large doses its action on the nervous system is very decided, producing vertigo, impaired vision, dilatation of the pupils, nausea, vomiting, and a reduction of the circulation, but no alarming narcotic effects. Three drops of the saturated tincture given every hour, for 20 hours, have been known to produce symptoms in every way simulating those of delirium tremens. Green tea is said to counteract its narcotic influences.
Library · King's American Dispensatory, vol. 1, 1898
CIMICIFUGA (U. S. P.)—CIMICIFUGA. Action, Medical Uses, and Dosage
Harvey Wickes Felter and John Uri Lloyd, p. 530. Transcribed from the page image on September 25, 2026, as printed.